Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery
نویسندگان
چکیده
منابع مشابه
Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery
BACKGROUND The ability to analyze the genomics of malignancies has opened up new possibilities for off-label targeted therapy in cancers that are refractory to standard therapy. At Mayo Clinic these efforts are organized through the Center for Individualized Medicine (CIM). RESULTS Prior to GTB, datasets were analyzed and integrated by a team of bioinformaticians and cancer biologists. Therap...
متن کاملBarriers to liposomal gene delivery: from application site to the target
AbstractGene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. One promising form of gene delivery system (DDS) is liposomes. The success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. Liposomal gene delivery systems...
متن کاملBarriers to liposomal gene delivery: from application site to the target
AbstractGene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. One promising form of gene delivery system (DDS) is liposomes. The success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. Liposomal gene delivery systems...
متن کاملFacilitators and Barriers to Adapting to the Disease: The Lived Experience of Patients with Multiple Sclerosis
Objective: Multiple sclerosis (MS) is a neurological disease in which the myelin lining the central nervous system is damaged. This study aimed to explore the experiences of facilitators and barriers adapting to MS. Material & Methods: This study was conducted using a qualitative phenomenological method. The participants were 14 (8 female and 6 male) referred to Rofideh Hospital in Tehran. Th...
متن کاملbarriers to liposomal gene delivery: from application site to the target
abstractgene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. one promising form of gene delivery system (dds) is liposomes. the success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. liposomal gene delivery systems...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.16057